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WHO Hyperplasia-EIN Concordance
Because EIN lesions are diagnosed using different criteria than WHO hyperplasias, the correlation is not fixed. Colored portions of Bar Graphs show approximate percentages of each WHO hyperplasia class that will be diagnosed as EIN. Remaining WHO hyperplasias not diagnostic of EIN (gray) will be allocated to unopposed estrogen (anovulatory), polyp, and other benign categories. Pie chart shows relative contributions of each hyperplasia type to the EIN diagnostic category in a biopsy series of sequential endometrial hyperplasias seen in a busy hospital practice. (Mutter, Baak, and Hecht, 2003)
●Atypical hyperplasias rediagnosed as EIN 70, 79, 616, 755, ●Complex Non-Atypical hyperplasias rediagnosed as EIN 59956, 59102
●Simple non-atypical hyperplasias rediagnosed as EIN 208, 342, 632, 996
●Hyperplasias not diagnosed as EIN Atypical hyperplasia rediagnosed as anovulatory 523, 945
Atypical hyperplasia rediagnosed as menstrual 129, 298, 453
Atypical hyperplasia rediagnosed as Polyp 290, 120, 847, 950
Atypical hyperplasia rediagnosed as Normal (Proliferative basalis) 16
Simple Non-atypical Hyperplasia rediagnosed as Polyp 4, 101, 155, 464, 603, 642, 665
Simple Non-atypical Hyperplasia rediagnosed as Anovulatory 62, 132, 171, 173, 223, 368, 427, 436, 578, 605, 664, 679, 756
Simple Non-atypical Hyperplasia rediagnosed as Normal Proliferative 268, 581, 753, 762, 765, 993
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Copyright 1998-2008 by George L. Mutter, MD. All Rights Reserved
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