| Case Number: |
|
59956 (PTEN series) |
| Original WHO Dx: |
|
complex non-atypical hyperplasia |
|
Comments: |
|
This localizing lesion is extremely sharply circumscribed,
with a cytology |
|
differing from the proliferative
background. It was considered "non-atypical" |
|
because of the polarized and
elongated nuclei. PTEN immunohistochemistry |
|
nicely shows the lesion
distribution and a genotypic-cytologic concordance. |
|
An example of an easily
identified EIN lesion that is difficult to interpret |
|
using traditional WHO criteria.
|
|